Code to Conception

Daily micro-protocols for the 90-day miracle window

| October 9, 2025 |

🔬 Pre-Bump Biology  

When anxiety spikes, your brain’s stress peptides (CRH, urocortin-2, RFRP-3) slam the brakes on kisspeptin—the master switch for ovulation. That means no LH surge, no egg release, no chance at conception. The fix isn’t wishful thinking: proven protocols can switch this surge back on within your 90-day window. 

🧬 Protocol Drop  

Today’s 1-Step Protocol: 

Perform 10 minutes of HRV-breathing (5.5–6 breaths per minute, nasal inhale, eyes closed) once per day, ideally mid-morning. Expect measurable reductions in anxiety and improved cycle regularity within 2–4 weeks—creating the hormonal environment your LH surge needs to fire.

👉 Read the full study summary

📚 Glossary Pop  

Kisspeptin: A brain hormone that acts like the “on switch” for fertility. It tells GnRH neurons to release signals that drive the LH surge, which triggers ovulation. Without kisspeptin firing correctly, your cycle stalls—even if everything else looks normal.

Want to learn more?

McCosh, R. B., Bell, H. F., Kreisman, M. J., Tian, K., & Breen, K. M. (2025). Suppression of luteinizing hormone secretion in female mice by a urocortin 2–CRHR2 signaling pathway. Endocrinology, 166(5), bqaf042. https://doi.org/10.1210/endocr/bqaf042 

Berga, S. L., Marcus, M. D., Loucks, T. L., Hlastala, S., Ringham, R., & Krohn, M. A. (2003). Recovery of ovarian activity in women with functional hypothalamic amenorrhea who were treated with cognitive behavioral therapy: A randomized controlled trial. Fertility and Sterility, 80(4), 976–981. https://doi.org/10.1016/S0015-0282(03)01124-5 

Szigeti, J. F., Kazinczi, C., Szabó, G., Sipos, M., Ujma, P. P., & Purebl, G. (2024). The clinical effectiveness of the Mind/Body Program for infertility on wellbeing and assisted reproduction outcomes: A randomized controlled trial in search for active ingredients. Human Reproduction, 39(8), 1735–1751. https://doi.org/10.1093/humrep/deae119