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Code to Conception

Daily micro-protocols for the 90-day miracle window

Day 13 of 90

| October 23, 2025 |

🔬 Pre-Bump Biology  

Oxidative stress quietly sabotages eggs and sperm—damaging membranes, DNA, and embryo potential. Two high-leverage levers counter it: micronutrient redox support (zinc + selenium powering SOD1/GPX4) and exposure control (cutting indoor EDCs that stoke ROS). Stack both to protect motility, fertilization, and early embryo quality.

🧬 Protocol Drop  

Today’s Allopathic Protocol:
Take 30 mg elemental zinc (picolinate or gluconate) + 200 µg selenium (selenomethionine) once daily for 90 days. Take zinc away from iron/calcium and antibiotics (≥2 h before or 4–6 h after). Do not exceed zinc 40 mg/day total from all sources.

Today’s Holistic Protocol:
For the next 90 days, swap all fragranced sprays/air fresheners and QAC-based disinfectants for fragrance-free, EPA Safer Choice options (e.g., 0.5–1.5% hydrogen peroxide or citric/lactic acid). Ventilate during/after cleaning, and HEPA vacuum 2–3×/week.

👉 Read the summary on zinc + selenium for pre-conception.
👉 Read the summary on safer cleaning swaps to cut EDCs.

📚 Glossary Pop  

Sperm DNA fragmentation (SDF): A measure of how many sperm carry broken DNA strands. Higher SDF is tied to lower fertilization rates, poorer embryo development, and miscarriage risk. Lowering oxidative stress (nutrients + cleaner indoor air) helps keep SDF in check.

Want to learn more?

Schisterman, E. F., Sjaarda, L. A., Clemons, T., Carrell, D., Perkins, N. J., Johnstone, E., … Diamond, M. P. (2020). Effect of folic acid and zinc supplementation in men on semen quality and live birth among couples undergoing infertility treatment: A randomized clinical trial. JAMA, 323(1), 35–48. https://doi.org/10.1001/jama.2019.18714

de Ligny, W. R., Smits, R. M., et al. (2025). Antioxidant treatment and the chance to conceive in men seeking fertility care (SUMMER randomized clinical trial). JAMA Network Open, 8(9), e2532405. https://doi.org/10.1001/jamanetworkopen.2025.32405

Alahmar, A. T. (2024). Effect of selenium (200 µg/day) on semen parameters in infertile men with and without varicocele. Journal of Experimental and Clinical Medicine, 607–609.

Yao, W., Zhang, Y., Zhao, Y., et al. (2023). Associations between phthalate metabolite concentrations in follicular fluid and reproductive outcomes among women undergoing IVF/ICSI. Environmental Health Perspectives, 131(12), 127019. https://doi.org/10.1289/EHP11998

Shen, J., Liu, R., Zhao, L., et al. (2024). Exposure of women undergoing in vitro fertilization to per- and polyfluoroalkyl substances: Evidence on negative effects on fertilization and high-quality embryos. Environmental Pollution, 359, 124474. https://doi.org/10.1016/j.envpol.2024.124474

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