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Myo-Inositol 4 g/day + 30-Second Cold Finish: The 90-Day Fertility Double

October 22, 2025

In partnership with

Code to Conception

Daily micro-protocols for the 90-day miracle window

Day 12 of 90

| October 22, 2025 |

🔬 Pre-Bump Biology  

 Insulin signaling shapes egg maturation and androgen balance, while temperature control protects sperm DNA. Pair myo-inositol (to sharpen insulin/FSH pathways and oocyte competence) with a brief cold-finish shower (for stress/immune tone) and strict heat avoidance—a double hit for egg quality and sperm health in your 90-day window.

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🧬 Protocol Drop  

 Today’s Allopathic Protocol:
Take myo-inositol 2,000 mg on waking + 2,000 mg 10–12 h later (total 4 g/day) for at least 90 days. Optional: add D-chiro-inositol 100 mg/day to achieve a 40:1 MI:DCI ratio.

Today’s Holistic Protocol:
End your morning shower with 30–60 seconds of the coldest tolerable water (~10–15 °C), 3–5×/week. Keep time-of-day consistent. Men: pair this with strict heat avoidance (no sauna/hot-tub; no heated seats/laptops on lap).

📚 Glossary Pop  

 MI:DCI 40:1 ratio: The most studied pairing of myo-inositol (MI) and D-chiro-inositol (DCI) in PCOS. This balance mirrors healthy follicular fluid, supporting insulin and FSH signaling that drive ovulation and egg maturation.

Forward this to your partner and sync your AM/PM doses + cold-finish routine. Conception is a team sport.
P.S. Tomorrow Teaser
The trace minerals that balance hormones and protect sperm DNA — plus the hidden fertility disruptors lurking under your kitchen sink.

Want to learn more?

Ravn, P., Glintborg, D., Andersen, M., Hagen, C., & Ravn, P. (2022). Myoinositol vs. metformin in women with polycystic ovary syndrome: A randomized controlled clinical trial. Metabolites, 12(12), 1183. https://doi.org/10.3390/metabo12121183

Fitz, V., Boyle, J., Arlt, W., & Joham, A. (2024). Inositol for polycystic ovary syndrome: A systematic review and meta-analysis to inform the 2023 update of the international evidence-based PCOS guidelines. The Journal of Clinical Endocrinology & Metabolism, 109(6), 1630–1656. https://doi.org/10.1210/clinem/dgad762

Buijze, G. A., Sierevelt, I. N., van der Heijden, B. C. J. M., Dijkgraaf, M. G. W., & Frings-Dresen, M. H. W. (2016). The effect of cold showering on health and work: A randomized controlled trial. PLOS ONE, 11(9), e0161749. https://doi.org/10.1371/journal.pone.0161749

Garolla, A., Torino, M., Sartini, B., Cosci, I., Patassini, C., Carraro, U., & Foresta, C. (2013). Seminal and molecular evidence that sauna exposure affects human spermatogenesis. Human Reproduction, 28(4), 877–885. https://doi.org/10.1093/humrep/det020

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